本题目来源于试卷: SL/HL Topic D1.3 Mutation and gene editing，类别为 IB生物学
[问答题]
6. Explain why a deletion mutation ( rm;wa*rxbsn;y2t e8* the re,a- bovn( h2 e4s 8h9sp/ypuwamoval of one base in the DNA base sequence of a gene) is likely toa-82 u9 hvps (bhwapy/4so ne, produce a protein which is non-functional.
参考答案: Deletion mutation is the removal/loss of a base from the DNA base sequence.
Deletion mutations can also be the loss of part of a chromosome/longer sequence of DNA.
The deletion alters the mRNA produced from the DNA base sequence.
The mRNA sequence will be affected from the deletion to the end of the gene.
The loss of base(s) will change the codons/there will be a frame shift (in the reading of the codons). The frame shift will affect a sequence of amino acids in the polypeptide chain.
The change in sequence of the amino acids will change the shape of the protein/make the protein non-functional.
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