题库网 (tiku.one)

 找回密码
 立即注册

 

      

上传图片附件

未使用图片

小贴士: 允许的图片文件格式为: gif, jpg, jpeg, png, webp,上传完成后会在上方生成预览,用鼠标连续双击缩略图,或拖动缩略图,该图片就被绑定至本题,显示在题目下方

本次作答已使用

小贴士: 此栏目显示的是当前作答使用的所有图片,绑定到某一题目的图片同时会显示在该题目下方; 删除使用的图片会将其转移到<未使用图片>类别


习题练习:Continuity and Change D.4 Cell & Nuclear Division



 作者: admin   总分: 64分  得分: _____________

答题人: 匿名未登录  开始时间: 24年01月11日 12:39  切换到: 整卷模式

标记此题
1#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  The graph below shows the relationship between maternal age and the inc73se+,eluc4(yp.pv q)d y dxcidence of non-disjunctix.d +s)pevceyq (,4pc lu 7d3yon. What relationship is suggested by the data in the graph?



参考答案:     查看本题详细解析

标记此题
2#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which stage of meiosisjuqebs8mro b+6 f08dkvm s,1 -nx1)y3ke tp m8 is represented in the diagram below?


参考答案:     查看本题详细解析

标记此题
3#
 
填空题 ( 1.0 分) 切至整卷模式 搜藏此题  
  The diagram below shows chromosomerkv: :mof:x16 gsmk:v q i3u z0pop48ps during meiosis.


1.Identify the stage of meiosis from the diagram.It is    I

2.State one process, other than the one shown in the diagram that promotes variation during meiosis.

3.State when the process you named in part (i) occurs in meiosis.It is    I

参考答案:     查看本题详细解析

标记此题
4#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which row correctly states (b) a72sglvy0qlae l5the number of alleles of a single gene which would be present in the nucleus of a cell as a result of each process7ev( slgy5a a )q20bll?

参考答案:     查看本题详细解析

标记此题
5#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which keyword is matched to the c9gr5bsoo sp+ n9mkis3;ee85p orrect definition?

参考答案:     查看本题详细解析

标记此题
6#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which statement(s) about mitosis is/arenk kmstq2 -b9t4osa)v,bqh27 true?
I. Sister chromatids are pulled apart during metaphase.
II. The nuclear envelope reforms during telophase.
III. Chromosomes supercoil and become visible during prophase.

参考答案:     查看本题详细解析

标记此题
7#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  In the micrograph below, which letter points tx- c8 wrzsk*7so a cell in anaphase?


参考答案:     查看本题详细解析

标记此题
8#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  During which stage ofloo x b/8bn( l5 0qy:dcnp,8vp mitosis does the nuclear envelope break down?

参考答案:     查看本题详细解析

标记此题
9#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which one of the following transport prote z v;94k1 r dai3bug(jisugl:*ins only carries out active transport?34gga:(9urd ; iikzjl*v bu1 s

参考答案:     查看本题详细解析

标记此题
10#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which process does not happen in the shoot4aza7gwweopn:9;2 i+hf a1 ka apex?

参考答案:     查看本题详细解析

标记此题
11#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which type/s of membra,k5oo)t kz npbs3 obp*0 s-ms2ne transport do/does not require energy expenditure?
I. Facilitated diffusion
II. Active transport
III. Osmosis

参考答案:     查看本题详细解析

标记此题
12#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  The diagram below represents a cell with a diploid numberfhzj0 uf,qd2 /-1 fgvt of 4. Which stage of cell divi dfhfg j0,v1t -qz2uf/sion is the cell currently undergoing?


参考答案:     查看本题详细解析

标记此题
13#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  The photomicrograph below shows a root tit7z jxb2tf k6ih2k/ ( -nc3gvsp meristem. Which of the following sentences correctly defines a meristeck3g vi(zs-6/ 2 jf2xt t7knbhm?


参考答案:     查看本题详细解析

标记此题
14#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  When does the random orientaiq u0q-jvh3 :vnva1uhm.j) l4tion of homologous chromosome pairs occur?

参考答案:     查看本题详细解析

标记此题
15#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which process does not occur during meiod08puka 7r h2asis?

参考答案:     查看本题详细解析

标记此题
16#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  If a cell with a diploid number of 9 -46e2wtbsm9 hhin wv36 undergoes mitosis, how many chromosomes will be present in ea9hhtenisv-46m b w w29ch daughter cell after cytokinesis?

参考答案:     查看本题详细解析

标记此题
17#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  The image shows a microgranea ;,;zi,bg tg8j, xfph of a cell.


What explains the appearance of the cell in the micrograph?

参考答案:     查看本题详细解析

标记此题
18#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which statement(s) about homologous chromosomzx8cnvuj8e9z(m4;b- d nzn.yfs7 x* v/vq2nmes is/are not true?
I. Homologous chromosomes have the same centromere position.
II. Homologous chromosomes have genes with the same loci.
III. Homologous chromosomes are identical to each other.

参考答案:     查看本题详细解析

标记此题
19#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  This karyogram is for an individual with Down syndrome.bui xr-qv x1:52vxd s*

Which statement is not correct?

参考答案:     查看本题详细解析

标记此题
20#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  In the cells of a horse (E. caballus) during prophase I of meiosis I thz, hf8 v9je+there are 64 chromosomes. Whatv ,jft9h+z eh8 is the haploid number of chromosomes?

参考答案:     查看本题详细解析

标记此题
21#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which arrow is pointingtlr45.w-aw gjt9 j 7ccb 4hj(s to a chiasma?


参考答案:     查看本题详细解析

标记此题
22#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  The diagram below represents the structure of a shoot apical merq 5qiiornrr6l1)+pe.u9 5l ie istem. Which row in the table correctly identifies the processes occuring in the structures .n91ee6li+iu5iroq )r 5r qlp labeled in the diagram?




参考答案:     查看本题详细解析

标记此题
23#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  How does meiosis promote vj+ 9jjcqb u7r m:+q/cb e1,cthqne /p9ariation?

参考答案:     查看本题详细解析

标记此题
24#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which of the following statements is/are h xiq o0icu k)cv(.v1,correct for meiosis?
I. It is a reduction division
II. It involves random orientation
III. It produces genetically identical cells

参考答案:     查看本题详细解析

标记此题
25#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  The diagram shows gametes produny +o*oi0l c0nced from two homologous chromosomes.


What single crossover event could have occurred to produce the gametes?
I. Crossover between Gene A and B
II. Crossover between Gene B and C
III. Crossover between Gene C and D

参考答案:     查看本题详细解析

标记此题
26#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which word describes the formation of secondary tumours from primb f68 ceyfdw;z1l iicr7.v9h* ary tumours as a result of the movement of9.*6beh;8z c7d wr1cfl yiifv cells?

参考答案:     查看本题详细解析

标记此题
27#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  How many chiasmata are pr2oe1b3 zs0o mcesent in the diagram?


参考答案:     查看本题详细解析

标记此题
28#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which statement is a similarity between cytokinesis ikh,i -l nf*z,)-1pe r8qbibdc n animal and plant cells?

参考答案:     查看本题详细解析

标记此题
29#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which stage of meiosis is matched to the correcgh*+ggfe .g ;zm sv +b1egy6o5t description?

参考答案:     查看本题详细解析

标记此题
30#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which statement(s) are true of meiosis i r91eck7 dr*cI but not meiosis II?
I. Crossing over occurs during prophase
II. Sister chromatids are pulled apart during anaphase
III. Chromosomes supercoil and become visible during prophase

参考答案:     查看本题详细解析

标记此题
31#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  The micrograph shows an oocyte after the first meiotic dn i8clc:j q sug4xj;wplp(l83 c:0q*eivision. This results in the formation of one large cell and one small cell. What is the fate of the n*48qpc l(ij 3j0cgq8exlc: ;p s:l uwlarge cell?



参考答案:     查看本题详细解析

标记此题
32#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which row correctly describk376, rpa qnyyes diploid and haploid cells in humans?

参考答案:     查看本题详细解析

标记此题
33#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  The following table shows the diploid chromosom c i9c2t4gcj* ms /w46;hmgp/f8kux ade number of a range of species.


Which of these statements is correct?

参考答案:     查看本题详细解析

标记此题
34#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  What conclusion can be drawn from the ckyo3 ) lgh9l r/w,t5zkk0zl0u)rkrz/a/4b e karyogram below?


参考答案:     查看本题详细解析

标记此题
35#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which of the following processes tp71v 328kizo qtdr 8qon/ m-yis characteristic of the meiotic and not the mitotic cell cycdoqo1kty /q pm382 iv8nrz 7t-le?

参考答案:     查看本题详细解析

标记此题
36#
 
填空题 ( 1.0 分) 切至整卷模式 搜藏此题  
  The diagram represents a bud with a shoot apifa ze0)zi+uaxo+1ven p45 .ccb(2e u 35epepf cal meristem.

1.State the type of cell division that occurs in the shoot apical meristem.
   is the type of cell division which occurs in the stem tip.
2.Outline what happens to the cells produced in the shoot apical meristem.

3.State two types of tissue that are produced by the differentiation of cells found at the shoot apical meristem

参考答案:     查看本题详细解析

标记此题
37#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  The diploid number of the chimpanzee (Pan troglodytes) is 48. Whichvzk5z kw( 3;.sg/5g(j msltwv row shows the correct chromosome number for different cell types and ww(5js3gvtzz /mg;(.5lskvk cell division stages?.

参考答案:     查看本题详细解析

标记此题
38#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  At the end of which phase of meiosi ;b4mra) koorv n0ww :-oe2j(zs I does crossing over occur, and what is the outcomewkb ovor02nzmr4;()wj: aoe - of crossing over?

参考答案:     查看本题详细解析

标记此题
39#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which of the following statet6j3b+cp7q( ogas e2ements does not describe a step in the sodium-potassium pump cycle in the neuronasj q27a6ee3gpb+toc(l cells?

参考答案:     查看本题详细解析

标记此题
40#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which row in the tabw0f aw,,b i x3:iw;5jv qji2qgle below is true of meiosis?

参考答案:     查看本题详细解析

标记此题
41#
 
问答题 ( 1.0 分) 切至整卷模式 搜藏此题  
Membrane transport is important for allowing particles to move acros/zp;a8 ph urzloqt 962s the cell membrane and respond to changes in the chemical composition of the extracellularz2 lz;6phpoq/8au 9rt fluid.

1.Outline the effects of placing a liver cell in a hypotonic solution.

2.Outline how the fluidity of membranes allows materials to be taken into cells or to be released from cells.

3.Compare and contrast four types of membrane transport. Include an example of each.
参考答案:    

标记此题
42#
 
问答题 ( 1.0 分) 切至整卷模式 搜藏此题  
1.Explain how mitosis is regulated :z z(m 3vrl(jtin cells.

2.Describe the stages of interphase and their importance to the process of mitosis.

3.Discuss the importance of mitosis to living organisms using named examples.
参考答案:    

标记此题
43#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  The diagram below shows the concentrationswxbv-toj.l+6e5q y5w.2n cbs of different cyclins during the cell cycle. Which cyclin is involved in preparing for DNA replicab.5ow ew2l6 .qb-xs +jt5vcyn tion?


参考答案:     查看本题详细解析

标记此题
44#
 
问答题 ( 1.0 分) 切至整卷模式 搜藏此题  
The diagram below shows chromosomes durn jlvp:kml8.t -xw-yig 6k;f3k s 55bting meiosis.

1.1.On the diagram above, label chiasma with the letter R.

1.2.On the diagram above, label a chromatid with the letter Q.

2.Describe the process of crossing over.

3.Explain how crossing over results in the formation of genetically unique nuclei.
参考答案:    

标记此题
45#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which stage of meiosis involves the separation ofy4x+mscy)knj adh8 ra107 v (y homologous chromosomes?

参考答案:     查看本题详细解析

标记此题
46#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  The mitotic index of throat tissues taken from 4 different paethi tg0 bj+9dqgn01: tients is shown below. Which patient is most likely to hjg :itb901h0 +q ngtedave cancerous throat tissue?

参考答案:     查看本题详细解析

标记此题
47#
 
问答题 ( 1.0 分) 切至整卷模式 搜藏此题  
1.Draw a labelled diagram to rel9ogvis0;b)7cmy2xb present the process of crossing over.

2.Compare and contrast random orientation and crossing over.

3.Outline the stages of meiosis.
参考答案:    

标记此题
48#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  The image shows an abnor )c) 7s5epknvzmal human karyotype.


What is the abnormality in this karyotype and its cause?


参考答案:     查看本题详细解析

标记此题
49#
 
问答题 ( 1.0 分) 切至整卷模式 搜藏此题  
The graph below shows the relative amount of DNA hncsb bbw+ga+g,p.2:i 4oyg5in one cell during one complete cey,wi+gn5g4: 2apgsc.b + obbhll cycle. Each letter represents one stage of the cell cycle.


1.1.State which stage of mitosis or interphase is represented by stage B in the graph.

1.2.Explain your answer to part (i).

1.3.Bortezomib is an anticancer medication and arrests cells in the G$_2$ phase. If a cell shown in this graph began the cell cycle at A with 3 relative units of DNA, and Bortezomib was applied to the cell culture at stage A as well, estimate the relative amount of DNA in the cell at the end of C.

2.Explain why the amount of DNA in one cell remains the same in stages C and D.


3.The diagram above shows cells in different stages of mitosis. Label one cell that is in prophase and one cell that is in anaphase.
参考答案:    

标记此题
50#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  The diagram below shows a cross between a matt9ywxo )x4)rle cat that is homozygous for brown, long49o t xt)xwyr) hair and a female cat that has black, short hair.


Which of the offspring has a recombinant genotype?


参考答案:     查看本题详细解析

标记此题
51#
 
问答题 ( 1.0 分) 切至整卷模式 搜藏此题  
1.Outline how polygenic traits 5t1ubgsczb4k 1gyrqd t+3.n 4 can show a normal distribution.

2.Outline the differences and similarities between homologous chromosomes.

3.Explain why expected and observed Mendelian ratios may differ.
参考答案:    

标记此题
52#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which gamete can result from the crossing over of non-si +g,e / slj(ym07l.twuxhes+ester chromatids shown in the e g0muye/+ jtx l,e7sshl(+ .wdiagram below?


参考答案:     查看本题详细解析

标记此题
53#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  The photomicrograph shows a pollen grain from L. candidum (Lily). Whicqzu+ddi /4 t(nh stage of meq zu4nt(dd+ /iiosis is shown?


参考答案:     查看本题详细解析

标记此题
54#
 
问答题 ( 1.0 分) 切至整卷模式 搜藏此题  
1.Outline the events which would lead to an individual beingb1b 4udhp5yd4 born with Down syndrome, which is charab hu45d4y1d pbcterised by the presence of three copies of chromosome 21.

2.Explain how meiosis increases variation.

3.Outline the stages of meiosis.
参考答案:    

标记此题
55#
 
问答题 ( 1.0 分) 切至整卷模式 搜藏此题  
The mitotic index is an indirect way of measuring plant growth..hr e*o8)kho pcg5vn ey-1o. n A study was conducted on white onions (Allium cepa), under controlled conditions in a lab, to investigate the effect of s)1hkhnno.e .ocg py-ro ev*5 8oil pH on the mitotic index of the roots.


1.Describe the trends shown in the graph.

2.Outline how the mitotic index is calculated.

3.Discuss whether the data support the hypothesis that onion plants should be grown in soil with a pH of 5.5.

4.Suggest how a pH of 9 affects the process of mitosis.

5.1.Explain why measuring the mitotic index in the root is an indirect way of measuring the overall growth rate of the onion plant.

5.2.Suggest another method, apart from measuring mitotic index, that could be used to measure plant growth.

6.State one of the variables that must be controlled to make this experiment valid.
参考答案:    

标记此题
56#
 
问答题 ( 1.0 分) 切至整卷模式 搜藏此题  
Mitosis and meiosis are two ways in which cells can divide. The diagrw7o:qn azd f3.ams below show two cells from an organism with a diploid number (7zwfa.dn3oq: 2n) of 8.


1.Deduce if Cell A is a gamete or a somatic cell. Justify your answer.

2.Identify the stage of meiosis represented in Cell B. Justify your answer.

3.1.Draw a diagram which represents Cell A during metaphase I.

3.2.Draw a diagram which represents Cell A during prophase II.

4.Compare and contrast meiosis and mitosis.
参考答案:    

标记此题
57#
 
问答题 ( 1.0 分) 切至整卷模式 搜藏此题  
1.Outline the role of gene expression in vm fiz. z-*+q9mj 7njplsx*t-stem growth.

2.Outline how growth is controlled in the shoot apex of plants.

3.Explain the process and applications of micropropagation.
参考答案:    

标记此题
58#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  The diagrams below show a cell, with a diploid number of 8, inkyh+ bb7rt 7toe:b9z2x6+7wyadeg t3 different stages of meiosis. Which robgt9ottewezy+ kdrb72y6b+ 77:hxa 3 w correctly names each stage?




参考答案:     查看本题详细解析

标记此题
59#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  The micrographs show foqjr a.ae;fy ;+87 idcuur phases of meiosis I in a plant. In what order do these phases occur?+q.id;7fac e;jy 8ra u


参考答案:     查看本题详细解析

标记此题
60#
 
问答题 ( 1.0 分) 切至整卷模式 搜藏此题  
Mitochondria are responsible for supplying metabolic energy in eukaryotic celh2k5 bp v :g9no qtf1rkq-2cg6ls. In most eukaryotes, which reproduce by sexual reproduction, mitochondrial DNA (mtDNA) is inherited from otgqr k2c1:hon5gk9fv p- 2b6qnly one of the parents: the mother in the case of humans. This is in contrast to nuclear DNA which is inherited from both parents. It has been suggested that, in some eukaryotic organisms, inheritance patterns of mtDNA found in hybrid cells, which are the result of sexual reproduction between two different yeast species, could be influenced by the parent’s genetic background.

In an experiment, scientists investigated if environmental factors could influence the inheritance of mtDNA in hybrid cells resulting from the sexual reproduction between two closely related species S. cerevisiae and S. paradoxus.

The first step in the experiment was to produce hybrid cells, which were then grown on different agar plates, each providing different growing conditions, which simulated different environmental stresses. Cultures were then taken from each agar plate and grown in a liquid medium, with the same respective environmental conditions. The procedure is outlined in the diagram below.


The mtDNA genotypes of the resulting hybrid cells were then identified and compared to that of the original parents.


1.Describe how the pattern of inheritance of mtDNA in the hybrid cells is affected by the different conditions.

2.Identify the liquid medium which resulted in the greatest AND smallest difference in number between hybrid cells with mtDNA from S.cerevisiae W303 and S paradoxus YDG197.

3.Calculate, for the 2% glucose condition, the percentage of hybrid cells which contained mtDNA genotypes of both S. cerevisiae and S. paradoxus.

4.Compare and contrast the results from the first and second experiments for the 2% glucose condition.

5.Identify the liquid medium condition which resulted in the greatest difference in the number of hybrid cells with mtDNA genotype from both parents between experiments 1 and 2.

In a final experiment, the team of scientists wanted to examine the activity of mitochondria, as indicated by respiratory competency, in the hybrid cells grown under each of the aforementioned growing conditions.
Respiratory competence was measured by using a stain, which stains respiratory competent cells red. The absorbance of cells was then measured, with higher absorbances indicating higher levels of respiratory competency.
Note that hybrid cells which contained both parents' mtDNA were excluded from this experiment.


6.State the growing condition and strain which resulted in the highest levels of mitochondrial activity.

7.Discuss the hypothesis that hybrid cells inherit the mtDNA from parents who are best adapted to their environment.

8.Evaluate the use of S. cerevisiae and related strains in the study of mtDNA inheritance in humans.
参考答案:    

标记此题
61#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  The table shows the number of cells in different stages of tk-k 5xl9,hpr ehe cell cycle in four samples of lung tissue from four patients. Which tissue has the lowest mitotic in,k-r exl 9k5hpdex?



参考答案:     查看本题详细解析

标记此题
62#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  The diagram shows the dominant cyqvyf k+the4 etxy1lr/ 83(s4 xclin/CDK complexes at different time points in the cell cycle. Which cyce+ lf1(hyq4s8t ex tkx4v3yr/lin/CDK complex activates DNA replication machinery?


参考答案:     查看本题详细解析

标记此题
63#
 
填空题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Studies have shown that genes such as Cyclin Dependent K n0to0m;( ygp2,q,wjrt oyhk ,enm k65inase 3 (CDKN3) are highly overexpressed in cervical tumours. oqk5,h(pkntn w, 0r;26 eytoj ,ymmg0


1.Calculate the percentage increase of CDKN3 gene expression in cancerous cervical tissue compared to healthy cervical tissue. Make sure you show your working.The number is   %.

Overexpression of CDKN3 in cervical tumours has been associated with decreased survival rates in cervical cancer patients and has been shown to trigger cells to exit mitosis and begin cytokinesis.


2.A hypothesis has been proposed that overexpression of CDKN3 in cervical tumours results in an increased chance of patient death. Evaluate the evidence for this using the data given.

3.Overexpression of CDKN3 results in increased levels of cell division. Describe how CDKs and cyclins are involved in the cell cycle.

4.CDKN3 has been identified as an oncogene. State the definition of an oncogene.

c-REL is another gene that has been linked to cervical cancer and its expression is correlated with the expression of CDKN3. Using CRISPR technology, cervical cancer cells have been created that do not express c-REL (c-REL -/-). Expression levels of c-REL were checked using protein analysis.


When c-REL is overexpressed in cervical epithelial cells it results in greater proliferation of cells and the cells spend less time in prometaphase (the phase between prophase and metaphase) compared to healthy cervical cells.


5.1.Looking at the photomicrograph above, identify the stage of mitosis that most of the cells are in.

5.2.Based on the evidence provided, suggest, with a reason, which of the labelled cells would be present in the highest numbers in c-REL -/- cervical cancer cells.

cREL-/- cervical cancer cells and cervical cancer cells with high expression levels of c-REL were treated with the chemotherapeutic drug, cisplatin. Both types of cells were exposed to different concentrations of cisplatin over a 21-hour period, and the effects on cell number were analysed.


6.Using the graph above, compare the response of cervical cancer cells that express c-REL and the cells that do not express c-REL (c-REL -/-) in response to exposure to different concentrations of cisplatin.

7.Suggest a reason for the different effects that cisplatin has on cervical cancer cells expressing c-REL and those that do not express c-REL (c-REL -/- ).

8.Suggest why some c-REL -/- cervical cancer cells have a similar level of cell death to those cervical cancer cells expressing c-REL.

9.Deduce whether cervical cancer cells expressing high levels of c-REL and CDKN3 will have a higher mitotic index than those with lower levels of c-REL and CDKN3..
Cervical cancer cells with a high expression of both genes will have a    mitotic index, as they are dividing more rapidly.

参考答案:     查看本题详细解析

标记此题
64#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  When is the concentration of cyclin E the highest during the cell z*4gd gprquez507 7grl ,i9yccycle ?


参考答案:     查看本题详细解析

  • :
  • 总分:64分 及格:38.4分 时间:不限时
    未答题: 已答题:0 答错题:
    当前第 题,此次习题练习共有 64 道题
    本系统支持习题练习,作业与考试三大模式,作业考试自动评分,成绩排序一键导出,可设定动态变量同一试卷千人千题
    如果您对本系统感兴趣,想加入我们或者想进行任何形式的合作,请加微信 skysky1258

    浏览记录|手机版首页|使用帮助|题库网 (https://tiku.one)

    GMT+8, 2025-7-8 14:56 , Processed in 0.310709 second(s), 149 queries , Redis On.