题库网 (tiku.one)

 找回密码
 立即注册

 

      

上传图片附件

未使用图片

小贴士: 允许的图片文件格式为: gif, jpg, jpeg, png, webp,上传完成后会在上方生成预览,用鼠标连续双击缩略图,或拖动缩略图,该图片就被绑定至本题,显示在题目下方

本次作答已使用

小贴士: 此栏目显示的是当前作答使用的所有图片,绑定到某一题目的图片同时会显示在该题目下方; 删除使用的图片会将其转移到<未使用图片>类别


习题练习:Continuity and Change D.4 Cell & Nuclear Division



 作者: admin   总分: 64分  得分: _____________

答题人: 匿名未登录  开始时间: 24年01月11日 12:39  切换到: 整卷模式

标记此题
1#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  The graph below shows the relationship between maternal age an6wrp,d6h .vym d the incidence of non-disjunction. W mwvhy.d 6pr6,hat relationship is suggested by the data in the graph?



参考答案:     查看本题详细解析

标记此题
2#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which stage of meiosis is r jie+k.yw q*t(epresented in the diagram below?


参考答案:     查看本题详细解析

标记此题
3#
 
填空题 ( 1.0 分) 切至整卷模式 搜藏此题  
  The diagram below shows 1:7 +s jv puz) p*dyy7s/;,gzvatuvfrchromosomes during meiosis.


1.Identify the stage of meiosis from the diagram.It is    I

2.State one process, other than the one shown in the diagram that promotes variation during meiosis.

3.State when the process you named in part (i) occurs in meiosis.It is    I

参考答案:     查看本题详细解析

标记此题
4#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which row correctly state0:+-1 x iu ft7e7txd:vu*nshzn qamf3s the number of alleles of a single gene which would be present in the nucleus of a cell as a result of each proce +:3 xa71s7 hffi*vn d mtxtz0uqn-e:uss?

参考答案:     查看本题详细解析

标记此题
5#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which keyword is matched to the correcii 8u8fptw2h)(t9qbyt definition?

参考答案:     查看本题详细解析

标记此题
6#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which statement(s) about mitosis is/arek6ohzft1 sh+xw5)rr ,n; gxf v::r1t i true?
I. Sister chromatids are pulled apart during metaphase.
II. The nuclear envelope reforms during telophase.
III. Chromosomes supercoil and become visible during prophase.

参考答案:     查看本题详细解析

标记此题
7#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  In the micrograph below, which letter points to azpiur7u 90 0xt trqpb.a2: 3mqei 7v3q cell in anaphase?


参考答案:     查看本题详细解析

标记此题
8#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  During which stage of mitosis does the*r 4ibai9-mnhe89hu(q(hli c nuclear envelope break down?

参考答案:     查看本题详细解析

标记此题
9#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which one of the following transport proteins only carries out active transport? 9c7imof ,k6 m0z8mngc,c yo:dnq8du;k,7mnoq 8 d f89uomdyg6c,c;ncz0: i m

参考答案:     查看本题详细解析

标记此题
10#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which process does not7vec e. +c+l wx*pjjc0 happen in the shoot apex?

参考答案:     查看本题详细解析

标记此题
11#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which type/s of membrane tra9q(tgp/t9toh nsport do/does not require energy expenditure?
I. Facilitated diffusion
II. Active transport
III. Osmosis

参考答案:     查看本题详细解析

标记此题
12#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  The diagram below repre,0b az jhq6ex,sents a cell with a diploid number of 4. Which stage of cell division is the cell currently undergz0xqea h,b j6,oing?


参考答案:     查看本题详细解析

标记此题
13#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  The photomicrograph below shows a root tip meristem. W3w.rmt.oj4e9 lg zth9 hich of the following sentences correctly defines a meristem? 4wt.. etg9hl rm9jz 3o


参考答案:     查看本题详细解析

标记此题
14#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  When does the random orienrrtp( 7v n)8jxtation of homologous chromosome pairs occur?

参考答案:     查看本题详细解析

标记此题
15#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which process does not occur during meiosis?)j1wf p-fhl a apa be*;,ltqf3 /4cbq6

参考答案:     查看本题详细解析

标记此题
16#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  If a cell with a diploid number of 36 undergoes mitosis, how many ch g9gq tn8fo* vj2z-we2romosomes will be present in each daughter cell aft t2gg9*q zj8wofnev-2 er cytokinesis?

参考答案:     查看本题详细解析

标记此题
17#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  The image shows a micrograph of a cell. ng-rmzgw/gz- ,8u laja0iis)49+ dva


What explains the appearance of the cell in the micrograph?

参考答案:     查看本题详细解析

标记此题
18#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which statement(s) about homologous chromosomes i 3qlt5ix 2aouh ;a dtl5b99r5us/are not true?
I. Homologous chromosomes have the same centromere position.
II. Homologous chromosomes have genes with the same loci.
III. Homologous chromosomes are identical to each other.

参考答案:     查看本题详细解析

标记此题
19#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  This karyogram is for an individual witx ,vrw8 h61vhfcs(u/znjo;5ycx9tj6h Down syndrome.

Which statement is not correct?

参考答案:     查看本题详细解析

标记此题
20#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  In the cells of a horse (E. caballus) during prophase I of meiosis I there6 pdk4qil84srdtka6tmc *b0 m ::ym)v are 6r4)0cdblv t8 6ti md:pqm:kym *aks46 4 chromosomes. What is the haploid number of chromosomes?

参考答案:     查看本题详细解析

标记此题
21#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which arrow is pointing 8 rnnv6-cmltv0u0 o6+odf8 ska /xzfi3/e .iuto a chiasma?


参考答案:     查看本题详细解析

标记此题
22#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  The diagram below represents the structure of a shoot apical meristem. Which zeebw46se 7aag,gypi/;*h c* row in the table correctly identifies the processes occuring in the structures labeled a ;g,e/wghye7c p*4azb*6 eisin the diagram?




参考答案:     查看本题详细解析

标记此题
23#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  How does meiosis promote xd-9ibpwjgt -5. kbtdc5-7k4psu ; atvariation?

参考答案:     查看本题详细解析

标记此题
24#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which of the following. frq xq1hz6j7 statements is/are correct for meiosis?
I. It is a reduction division
II. It involves random orientation
III. It produces genetically identical cells

参考答案:     查看本题详细解析

标记此题
25#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  The diagram shows gametes produced from two homologouj 0.grv/j3xw2uf zwk y /:ippy,ao 3l9s chromosomes.


What single crossover event could have occurred to produce the gametes?
I. Crossover between Gene A and B
II. Crossover between Gene B and C
III. Crossover between Gene C and D

参考答案:     查看本题详细解析

标记此题
26#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which word describes the formation of secondary tumours from prirci3yq-gpi8x 1hm:xs a1(lt hps j:s780a .ismary tumours as a result of the movemeh.0itl jh7 ai:a yi1qs8 p3-p rxg1x(c ss8sm:nt of cells?

参考答案:     查看本题详细解析

标记此题
27#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  How many chiasmata are present in the diag 2p9c2lqks h lq(--iearam?


参考答案:     查看本题详细解析

标记此题
28#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which statement is a similarity between cytokinesis in an/jeyz 0g sr3k(-k/0nwpgp hf) imal and plant cells?

参考答案:     查看本题详细解析

标记此题
29#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which stage of meiosis 8v ra84qxlq5iis matched to the correct description?

参考答案:     查看本题详细解析

标记此题
30#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which statement(s) are true of meiosis I benm ;hj um ;v3+bg kkh10t5;yaut not meiosis II?
I. Crossing over occurs during prophase
II. Sister chromatids are pulled apart during anaphase
III. Chromosomes supercoil and become visible during prophase

参考答案:     查看本题详细解析

标记此题
31#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  The micrograph shows an oocyte after the firs*l7vw p fah;m+t meiotic division. This results in the formation of one large cell and one small cell. What is the fate of the large wp *havmf l;+7cell?



参考答案:     查看本题详细解析

标记此题
32#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which row correctly describes diploid and haploid cells in s2ebzv4 8tk(r/ue / sghumans?

参考答案:     查看本题详细解析

标记此题
33#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  The following table shows the diploid chromosome number of a w21,/ (wzb0el3 hweo relxbb ,range of species.


Which of these statements is correct?

参考答案:     查看本题详细解析

标记此题
34#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  What conclusion can be drawn from the ka dv f+/ahm2gwzpxwfw 5*- 7kg0ryogram below?


参考答案:     查看本题详细解析

标记此题
35#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which of the following x.t2mfbq9 7f8d1y +qdhxty o2processes is characteristic of the meiotic and not the mitotic y 9 q7d8y1odft+.b tq2x fx2hmcell cycle?

参考答案:     查看本题详细解析

标记此题
36#
 
填空题 ( 1.0 分) 切至整卷模式 搜藏此题  
  The diagram represents a bud with a shoot apical meriste(p* :kd,t3 2j munf4g(biuu)ysy n dh(wou0/i m.

1.State the type of cell division that occurs in the shoot apical meristem.
   is the type of cell division which occurs in the stem tip.
2.Outline what happens to the cells produced in the shoot apical meristem.

3.State two types of tissue that are produced by the differentiation of cells found at the shoot apical meristem

参考答案:     查看本题详细解析

标记此题
37#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  The diploid number of the chimpanzee (Pan troglodytes) is 48. Which row*d vcv4q2z*8v;zph bb shows the correct chromosome numbevzzbcqbdv *8 *4p vh2;r for different cell types and cell division stages?.

参考答案:     查看本题详细解析

标记此题
38#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  At the end of which phase of meiosis I does crossing over /q 46gm0 vjwpwdk)bl: u. rb-voccur, and what is the outcome of crossing ovedklgw :mpj bq6-w vrb0/v) .u4r?

参考答案:     查看本题详细解析

标记此题
39#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which of the following statemenzv ygb0gud( vvp-ks/fwrr 80 e4.z4* ots does not describe a step in the sodium-potassium pump cycle i8s(vb.0 zzevg v*-ogkp0/u f4 4wdyr rn the neuronal cells?

参考答案:     查看本题详细解析

标记此题
40#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which row in the table below is true of meio:gvhzftz (k/*e pm8bj+q wg-) vn*z e6sis?

参考答案:     查看本题详细解析

标记此题
41#
 
问答题 ( 1.0 分) 切至整卷模式 搜藏此题  
Membrane transport is important for allowing particles to move across the cvc /ik5c7vw 9nell membrane and respond to changes in the chemical composition of thev9cn7k/wi 5c v extracellular fluid.

1.Outline the effects of placing a liver cell in a hypotonic solution.

2.Outline how the fluidity of membranes allows materials to be taken into cells or to be released from cells.

3.Compare and contrast four types of membrane transport. Include an example of each.
参考答案:    

标记此题
42#
 
问答题 ( 1.0 分) 切至整卷模式 搜藏此题  
1.Explain how mitosis is regulated in g;31 )l3z (bp2avazygl4cq 6z*vw lwycells.

2.Describe the stages of interphase and their importance to the process of mitosis.

3.Discuss the importance of mitosis to living organisms using named examples.
参考答案:    

标记此题
43#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  The diagram below shows the concentrations of different cyclins during thg.emb4 ww6baw:b j7l1 e cell cycle. Which cyclin is involved in pr76ewg:bm4 ja. bb w1wleparing for DNA replication?


参考答案:     查看本题详细解析

标记此题
44#
 
问答题 ( 1.0 分) 切至整卷模式 搜藏此题  
The diagram below shows c+mp. 2i-18mvac m1rlv xg:q q6mk-i6z qagq4lhromosomes during meiosis.

1.1.On the diagram above, label chiasma with the letter R.

1.2.On the diagram above, label a chromatid with the letter Q.

2.Describe the process of crossing over.

3.Explain how crossing over results in the formation of genetically unique nuclei.
参考答案:    

标记此题
45#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which stage of meiosis involves the s-e 8;sx g.vhdpeparation of homologous chromosomes?

参考答案:     查看本题详细解析

标记此题
46#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  The mitotic index of throat tissues taken fromu :(7edo(omcr tbs 9f5 4 different patients is shown below. Which patientce (obumf:s 7( to5rd9 is most likely to have cancerous throat tissue?

参考答案:     查看本题详细解析

标记此题
47#
 
问答题 ( 1.0 分) 切至整卷模式 搜藏此题  
1.Draw a labelled diagram to represent the process of crossing ove+b9ow*lp1evz r.

2.Compare and contrast random orientation and crossing over.

3.Outline the stages of meiosis.
参考答案:    

标记此题
48#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  The image shows an abnoks6ba./ u-aformal human karyotype.


What is the abnormality in this karyotype and its cause?


参考答案:     查看本题详细解析

标记此题
49#
 
问答题 ( 1.0 分) 切至整卷模式 搜藏此题  
The graph below shows the relative amount of DNA in one cell durvmkgkmqz p pc5,. x,96(p: rmsing one complete cell cycle. Each letter represents one stskckm:gxqvz .p(,mp,59 mp6 rage of the cell cycle.


1.1.State which stage of mitosis or interphase is represented by stage B in the graph.

1.2.Explain your answer to part (i).

1.3.Bortezomib is an anticancer medication and arrests cells in the G$_2$ phase. If a cell shown in this graph began the cell cycle at A with 3 relative units of DNA, and Bortezomib was applied to the cell culture at stage A as well, estimate the relative amount of DNA in the cell at the end of C.

2.Explain why the amount of DNA in one cell remains the same in stages C and D.


3.The diagram above shows cells in different stages of mitosis. Label one cell that is in prophase and one cell that is in anaphase.
参考答案:    

标记此题
50#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  The diagram below shows a cross betwee 4ew:xy iin9sz/pt.b(8lh(ud n a male cat that is homozygous for brown, long hair and a female cat tha 8zlt:sbxp.yd h i((i4 n9uwe/t has black, short hair.


Which of the offspring has a recombinant genotype?


参考答案:     查看本题详细解析

标记此题
51#
 
问答题 ( 1.0 分) 切至整卷模式 搜藏此题  
1.Outline how polygenic traits can show a normal dz :lqwg2y e-p *t(i9ha;y j6ldistribution.

2.Outline the differences and similarities between homologous chromosomes.

3.Explain why expected and observed Mendelian ratios may differ.
参考答案:    

标记此题
52#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Which gamete can result from the crossing over of non-sister chroyrw-+qc3 wf yba*9vb*matids shown in the d*yqbw *+3rcw-va yf9biagram below?


参考答案:     查看本题详细解析

标记此题
53#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  The photomicrograph shows +2* op1gj azv*fxps/ ta pollen grain from L. candidum (Lily). Which stage of meiosis is shows1px z+ vf*oapg/2t* jn?


参考答案:     查看本题详细解析

标记此题
54#
 
问答题 ( 1.0 分) 切至整卷模式 搜藏此题  
1.Outline the events which would lead to an individual beim;dot5go2 jur:t1,b/zk8un o ng born with Down syndrome, which is characterised by the presenceb5r zudn jom8/,21kttgoo; u : of three copies of chromosome 21.

2.Explain how meiosis increases variation.

3.Outline the stages of meiosis.
参考答案:    

标记此题
55#
 
问答题 ( 1.0 分) 切至整卷模式 搜藏此题  
The mitotic index is an indirect way of measuring .kj3vjg:u c vsi 6 9 e3qj:e3c5ytike0plant growth. A study was conducted on white onions (Allium cepa), under controlled conditions in a lab, to investigate the effect of soil pH on the mitotic indexk yu g6 ic.jq:j:0kc3 iv jsv9ee3e5t3 of the roots.


1.Describe the trends shown in the graph.

2.Outline how the mitotic index is calculated.

3.Discuss whether the data support the hypothesis that onion plants should be grown in soil with a pH of 5.5.

4.Suggest how a pH of 9 affects the process of mitosis.

5.1.Explain why measuring the mitotic index in the root is an indirect way of measuring the overall growth rate of the onion plant.

5.2.Suggest another method, apart from measuring mitotic index, that could be used to measure plant growth.

6.State one of the variables that must be controlled to make this experiment valid.
参考答案:    

标记此题
56#
 
问答题 ( 1.0 分) 切至整卷模式 搜藏此题  
Mitosis and meiosis are two ways i9*k3seaa23 gemqx t,zn which cells can divide. The diagrams below show two cells from an organism with a diploid number (2n) of 8qk tese*a39xz am2g3 ,.


1.Deduce if Cell A is a gamete or a somatic cell. Justify your answer.

2.Identify the stage of meiosis represented in Cell B. Justify your answer.

3.1.Draw a diagram which represents Cell A during metaphase I.

3.2.Draw a diagram which represents Cell A during prophase II.

4.Compare and contrast meiosis and mitosis.
参考答案:    

标记此题
57#
 
问答题 ( 1.0 分) 切至整卷模式 搜藏此题  
1.Outline the role of gene sxu ;.fo3a bu7expression in stem growth.

2.Outline how growth is controlled in the shoot apex of plants.

3.Explain the process and applications of micropropagation.
参考答案:    

标记此题
58#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  The diagrams below show a cell, with a diploid number of 8, tt(q c3n. ihk;in different stages of meiosis. Which row cor.3ntt ki;h(c qrectly names each stage?




参考答案:     查看本题详细解析

标记此题
59#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  The micrographs show four phases of meiosis I in a plant. In whaeq+ 4 ef3yjo86ov gv 45nncwl3t order do these phases occgv ny 8oq46 jcv 3e4o3nwf+e5lur?


参考答案:     查看本题详细解析

标记此题
60#
 
问答题 ( 1.0 分) 切至整卷模式 搜藏此题  
Mitochondria are respong(4v*1wyss 6) x magchsible for supplying metabolic energy in eukaryotic cells. In most eukaryotes, which reproduce by sexual reproduction, mitochondrial DNA (mtDNA) is inherited from only one of the parents: the mother in the case of humans. This is in contrast to nuclear DNA which is inherited from both parents. It has been suggested that, in some eukaryotic organisms, inheritance patterns of mtDNA found in hybrid cells, which are the result of sexual reproduction between two different yeast species, could be influenced by the parent’s genet a)*6sm( sgwcyg1xh4vic background.

In an experiment, scientists investigated if environmental factors could influence the inheritance of mtDNA in hybrid cells resulting from the sexual reproduction between two closely related species S. cerevisiae and S. paradoxus.

The first step in the experiment was to produce hybrid cells, which were then grown on different agar plates, each providing different growing conditions, which simulated different environmental stresses. Cultures were then taken from each agar plate and grown in a liquid medium, with the same respective environmental conditions. The procedure is outlined in the diagram below.


The mtDNA genotypes of the resulting hybrid cells were then identified and compared to that of the original parents.


1.Describe how the pattern of inheritance of mtDNA in the hybrid cells is affected by the different conditions.

2.Identify the liquid medium which resulted in the greatest AND smallest difference in number between hybrid cells with mtDNA from S.cerevisiae W303 and S paradoxus YDG197.

3.Calculate, for the 2% glucose condition, the percentage of hybrid cells which contained mtDNA genotypes of both S. cerevisiae and S. paradoxus.

4.Compare and contrast the results from the first and second experiments for the 2% glucose condition.

5.Identify the liquid medium condition which resulted in the greatest difference in the number of hybrid cells with mtDNA genotype from both parents between experiments 1 and 2.

In a final experiment, the team of scientists wanted to examine the activity of mitochondria, as indicated by respiratory competency, in the hybrid cells grown under each of the aforementioned growing conditions.
Respiratory competence was measured by using a stain, which stains respiratory competent cells red. The absorbance of cells was then measured, with higher absorbances indicating higher levels of respiratory competency.
Note that hybrid cells which contained both parents' mtDNA were excluded from this experiment.


6.State the growing condition and strain which resulted in the highest levels of mitochondrial activity.

7.Discuss the hypothesis that hybrid cells inherit the mtDNA from parents who are best adapted to their environment.

8.Evaluate the use of S. cerevisiae and related strains in the study of mtDNA inheritance in humans.
参考答案:    

标记此题
61#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  The table shows the number of cells in different stages of the6r;.; wzwo.tx mm/gw r cell cycle in four samples of lung tissue from four patients. Which tissue has the lowewgotr; .;mz/wx .6mrwst mitotic index?



参考答案:     查看本题详细解析

标记此题
62#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  The diagram shows the dominant cyclin/CDK complexes at different tyojy zy5s c(fn.0 s) hq4:2naeime points in the cell cycle. Whichh. :yy c(5s2sf4n yjan0 zoeq) cyclin/CDK complex activates DNA replication machinery?


参考答案:     查看本题详细解析

标记此题
63#
 
填空题 ( 1.0 分) 切至整卷模式 搜藏此题  
  Studies have shown that genes such as Cyclin Dependent Kinase 3+l27gpk5hm4r y oe o)o (CDKN3) are highly overexpressed in cer)komy 7hlp4o5+2 g oervical tumours.


1.Calculate the percentage increase of CDKN3 gene expression in cancerous cervical tissue compared to healthy cervical tissue. Make sure you show your working.The number is   %.

Overexpression of CDKN3 in cervical tumours has been associated with decreased survival rates in cervical cancer patients and has been shown to trigger cells to exit mitosis and begin cytokinesis.


2.A hypothesis has been proposed that overexpression of CDKN3 in cervical tumours results in an increased chance of patient death. Evaluate the evidence for this using the data given.

3.Overexpression of CDKN3 results in increased levels of cell division. Describe how CDKs and cyclins are involved in the cell cycle.

4.CDKN3 has been identified as an oncogene. State the definition of an oncogene.

c-REL is another gene that has been linked to cervical cancer and its expression is correlated with the expression of CDKN3. Using CRISPR technology, cervical cancer cells have been created that do not express c-REL (c-REL -/-). Expression levels of c-REL were checked using protein analysis.


When c-REL is overexpressed in cervical epithelial cells it results in greater proliferation of cells and the cells spend less time in prometaphase (the phase between prophase and metaphase) compared to healthy cervical cells.


5.1.Looking at the photomicrograph above, identify the stage of mitosis that most of the cells are in.

5.2.Based on the evidence provided, suggest, with a reason, which of the labelled cells would be present in the highest numbers in c-REL -/- cervical cancer cells.

cREL-/- cervical cancer cells and cervical cancer cells with high expression levels of c-REL were treated with the chemotherapeutic drug, cisplatin. Both types of cells were exposed to different concentrations of cisplatin over a 21-hour period, and the effects on cell number were analysed.


6.Using the graph above, compare the response of cervical cancer cells that express c-REL and the cells that do not express c-REL (c-REL -/-) in response to exposure to different concentrations of cisplatin.

7.Suggest a reason for the different effects that cisplatin has on cervical cancer cells expressing c-REL and those that do not express c-REL (c-REL -/- ).

8.Suggest why some c-REL -/- cervical cancer cells have a similar level of cell death to those cervical cancer cells expressing c-REL.

9.Deduce whether cervical cancer cells expressing high levels of c-REL and CDKN3 will have a higher mitotic index than those with lower levels of c-REL and CDKN3..
Cervical cancer cells with a high expression of both genes will have a    mitotic index, as they are dividing more rapidly.

参考答案:     查看本题详细解析

标记此题
64#
 
单选题 ( 1.0 分) 切至整卷模式 搜藏此题  
  When is the concentration of comu 6sq9ie: *gca 6cf2yclin E the highest during the cell cycle ?


参考答案:     查看本题详细解析

  • :
  • 总分:64分 及格:38.4分 时间:不限时
    未答题: 已答题:0 答错题:
    当前第 题,此次习题练习共有 64 道题
    本系统支持习题练习,作业与考试三大模式,作业考试自动评分,成绩排序一键导出,可设定动态变量同一试卷千人千题
    如果您对本系统感兴趣,想加入我们或者想进行任何形式的合作,请加微信 skysky1258

    浏览记录|使用帮助|手机版|切到手机版|题库网 (https://tiku.one)

    GMT+8, 2025-4-25 22:53 , Processed in 0.334845 second(s), 150 queries , Redis On.