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习题练习:SL/HL Topic D1.3 Mutation and gene editing



 作者: admin   总分: 12分  得分: _____________

答题人: 匿名未登录  开始时间: 25年02月01日 01:10  切换到: 整卷模式

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1#
 
单选题 ( 1.0 分) (组内1/4) 切至整卷模式 搜藏此题  
第 1 题组 (共 4 题 4 分)
  1. Which of the follvl gv)h.ltvw :m ch.2ez 4/2eak36xrc owing is not a type of mutation?

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2#
 
单选题 ( 1.0 分) (组内2/4) 切至整卷模式 搜藏此题  
  2. What is the role of mutation in a poblmu1y4:7 , lhv 8watq1mqwi 52 qku-wpulation?

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3#
 
单选题 ( 1.0 分) (组内3/4) 切至整卷模式 搜藏此题  
  3. Which of the following are regarded as possible causes ozf7ro,6kg7zeq a )8vs f mutations in DNA?
I. Errors in DNA replication.
II. Mutagenic chemicals.
III. Advantageous traits in a parent.
IV. Some forms of radiation.

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4#
 
单选题 ( 1.0 分) (组内4/4) 切至整卷模式 搜藏此题  
  4. Single nucleotide polymorphisms95d8evr1rd0 eul-l lj (SNPs) are a form of mutation. Which of the follow5dj089rle 1r ud-ellving is the best description of an SNP in the DNA base sequence?

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5#
 
问答题 ( 1.0 分) (组内1/4) 切至整卷模式 搜藏此题  
第 2 题组 (共 4 题 4 分) 当前第1/4题
题组内容描述:
5. The HTT gene in humans is found on human chromosome 4 at position 16.3. It is unusual in that the gene has a repeating sequence of the triplet CAG which translates to the amino acid glutamine. The repeating sequences occur at the beginning of the gene and the number of these trinucleotide repeats varies, if it is between 7 and 35, there is no effect on the individual, but a greater number of repeats can lead to the Huntingtin protein being non-functional and to cause developmental problems in those who possess this variant of the gene, resulting in an inherited condition, known as Huntington disease. The severity of the disease is linked to the number of trinucleotide repeats.
a. Deduce the kind of mutation responsible for t; adxv9r- kb nyl:+6xzl1.fy ghis condition
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6#
 
问答题 ( 1.0 分) (组内2/4) 切至整卷模式 搜藏此题  
第 2 题组 (共 4 题 4 分) 当前第2/4题
题组内容描述:
5. The HTT gene in humans is found on human chromosome 4 at position 16.3. It is unusual in that the gene has a repeating sequence of the triplet CAG which translates to the amino acid glutamine. The repeating sequences occur at the beginning of the gene and the number of these trinucleotide repeats varies, if it is between 7 and 35, there is no effect on the individual, but a greater number of repeats can lead to the Huntingtin protein being non-functional and to cause developmental problems in those who possess this variant of the gene, resulting in an inherited condition, known as Huntington disease. The severity of the disease is linked to the number of trinucleotide repeats.
b. Explain how a mutation increasing the number of CAG repeb2.tnjj d.-y ng +4frpats would alter the polypeptide sequence of the Hd .t.gnbjr2p4 f-nyj+TT protein.
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7#
 
问答题 ( 1.0 分) (组内3/4) 切至整卷模式 搜藏此题  
第 2 题组 (共 4 题 4 分) 当前第3/4题
题组内容描述:
5. The HTT gene in humans is found on human chromosome 4 at position 16.3. It is unusual in that the gene has a repeating sequence of the triplet CAG which translates to the amino acid glutamine. The repeating sequences occur at the beginning of the gene and the number of these trinucleotide repeats varies, if it is between 7 and 35, there is no effect on the individual, but a greater number of repeats can lead to the Huntingtin protein being non-functional and to cause developmental problems in those who possess this variant of the gene, resulting in an inherited condition, known as Huntington disease. The severity of the disease is linked to the number of trinucleotide repeats.
c. The image shows the HTT protein in an individual with 30 rep5 wiv: 8obr q-thr12yb2db/ fzeats:

This protein has 30 CAG repeats and functions normally.
Suggest how the addition of 120 glutamine amino acid molecules to this HTT protein might cause the protein to become non-functional.
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8#
 
问答题 ( 1.0 分) (组内4/4) 切至整卷模式 搜藏此题  
第 2 题组 (共 4 题 4 分) 当前第4/4题
题组内容描述:
5. The HTT gene in humans is found on human chromosome 4 at position 16.3. It is unusual in that the gene has a repeating sequence of the triplet CAG which translates to the amino acid glutamine. The repeating sequences occur at the beginning of the gene and the number of these trinucleotide repeats varies, if it is between 7 and 35, there is no effect on the individual, but a greater number of repeats can lead to the Huntingtin protein being non-functional and to cause developmental problems in those who possess this variant of the gene, resulting in an inherited condition, known as Huntington disease. The severity of the disease is linked to the number of trinucleotide repeats.
d. The mutation is inherited if it occ)r- in,mzj4woy(u2is xkkb)g 63 /rvturs in germ cells of the parent.
Distinguish between germ line mutations and somatic mutations.
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9#
 
问答题 ( 1.0 分) (组内1/4) 切至整卷模式 搜藏此题  
第 3 题组 (共 4 题 4 分)
6. Explain why a deletion mutation (the removal of one base in t.p6r. 8mqgk2z; mc b,jcdh8 mzhe DNA base sequence of a gene) is likely to produce azg,j2hk;8z 6m c.mcq r.mdp8b protein which is non-functional.
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10#
 
问答题 ( 1.0 分) (组内2/4) 切至整卷模式 搜藏此题  
7. Discuss the role of mutam.er 9vvfqa kpw3.3 x qg7++pwbj, m2ntion in evolution of new characteristics in a species.+9wm kgfp mqr e3 q2.wvb.3nx+ v,pja7
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11#
 
问答题 ( 1.0 分) (组内3/4) 切至整卷模式 搜藏此题  
8. Suggest two hypotheses for the presence in many species of highly conserved cj-d vwruekq.eyb-;- t fes,6o4ay66 hzt,;dDNA sequences, that have cha ;cut y6ar .,-vowsd ej6q-64h;fyb,tek- zdenged very little during evolution.
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12#
 
问答题 ( 1.0 分) (组内4/4) 切至整卷模式 搜藏此题  
9. Outline how gene knldier:0 cbp m08-hk4r08t ea, sc r,adockout can aid scientists to determine the function of a gerhipe,l4:00a0 mdatkecc , rds8 8br-ne.
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